HitPredict

Interactor 1: Q0VAV5 (Q0VAV5)
RAS protein activator like 2
Gene: Rasal2

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0005096 - GTPase activator activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1268 Mm			1 1186
+	Mm
		93233 E9PW37_MOUSE (1-1268): 0: 1246: 99.92		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112542 DAB2P_MOUSE (134-1267): 0: 937: 56.48		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		99969 SYGP1_MOUSE (44-1267): 0: 855: 42.68		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Hs
		1355995 NGAP_HUMAN (134-1268): 0: 1044: 97.36		AGAP1_HUMAN (384-1145): 0: 713: 53.70
+	Mm
		93411 SYGP1_MOUSE (44-1267): 0: 855: 42.68		E9Q3K3_MOUSE (80-1145): 0: 783: 43.63
+	Mm
		100045 SYGP1_MOUSE (44-1267): 0: 855: 42.68		AGAP1_MOUSE (384-1145): 0: 710: 53.70
+	Mm
		1112670 RASL1_MOUSE (206-901): 1.62e-162: 507: 18.09		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		99872 F6QQP6_MOUSE (461-1238): 1.24e-161: 501: 49.56		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		99881 SYGP1_MOUSE (44-1267): 0: 855: 42.68		F8VQE9_MOUSE (384-1150): 0: 660: 51.54
+	Mm
		1112565 IQGA2_MOUSE (247-888): 1.25e-141: 470: 14.42		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		1112651 IQGA1_MOUSE (270-895): 2.89e-131: 443: 12.33		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		980214 NF1_MOUSE (422-710): 9.69e-88: 317: 28.13		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		100015 SYGP1_MOUSE (44-1267): 0: 855: 42.68		ASAP2_MOUSE (690-1168): 1.01e-99: 341: 21.08
+	Mm
		88329 SYGP1_MOUSE (44-1267): 0: 855: 42.68		D3YX85_MOUSE (690-1168): 1.11e-97: 335: 21.08
+	Mm
		100001 SYGP1_MOUSE (44-1267): 0: 855: 42.68		GIT1_MOUSE (932-1139): 6.25e-72: 258: 32.88
+	Hs
		598546 NF1_HUMAN (422-710): 6.65e-88: 317: 27.81		AGAP1_HUMAN (384-1145): 0: 713: 53.70
+	Hs
		809252 IQGA1_HUMAN (270-895): 1.25e-129: 439: 12.33		RAP1A_HUMAN (398-567): 1.81e-70: 235: 23.03
+	Hs
		596403 RASA1_HUMAN (220-751): 4.27e-141: 457: 26.13		ACAP2_HUMAN (634-1166): 2.28e-51: 197: 13.44
+	Sc
		533758 BUD2_YEAST (232-728): 4.21e-112: 380: 22.72		RSR1_YEAST (398-656): 8.23e-79: 262: 17.91