HitPredict

Interactor 1: LTOR4 (Q0VGL1)
Ragulator complex protein LAMTOR4 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4) [Cleaved into: Ragulator complex protein LAMTOR4, N-terminally processed]
Gene: LAMTOR4

Interactor 2: RRAGB (Q5VZM2)
Ras-related GTP-binding protein B (Rag B) (RagB) (EC 3.6.5.-)
Gene: RRAGB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 22980980, 25561175
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0032008 - positive regulation of TOR signaling GO:0071230 - cellular response to amino acid stimulus GO:1904263 - positive regulation of TORC1 signaling
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 99 Hs			1 374
+	Hs
		1012666 LTOR4_HUMAN (1-99): 3.15e-57: 172: 100.00		RRAGA_HUMAN (34-374): 3.2e-179: 501: 90.03
+	Hs
		1012679 LTOR4_HUMAN (1-99): 3.15e-57: 172: 100.00		RRAGD_HUMAN (20-296): 1.09e-103: 313: 26.06
+	Hs
		1012678 LTOR4_HUMAN (1-99): 3.15e-57: 172: 100.00		RRAGC_HUMAN (38-296): 1.57e-95: 292: 26.42