HitPredict

Interactor 1: VPS2B (Q0WTY4)
Vacuolar protein sorting-associated protein 2 homolog 2 (AtVPS2-2) (Charged multivesicular body protein 2 homolog 2) (ESCRT-III complex subunit VPS2 homolog 2)
Gene: VPS2.2

Interactor 2: VP601 (Q9LPN5)
Vacuolar protein sorting-associated protein 60.1
Gene: VPS60-1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.762

Property	Details
Experiments	22010978
Identification Methods	affinity chromatography technology, protein complementation assay, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0005771 - multivesicular body GO:0015031 - protein transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 222 At			1 235
+	Ce
		1090380 Q9U2F6_CAEEL (3-221): 7.98e-54: 174: 31.33		Q18886_CAEEL (2-221): 5.05e-39: 136: 21.36
+	Dm
		1371192 Q9VN02_DROME (1-220): 1.53e-50: 165: 24.32		CHMP5_DROME (1-231): 1.28e-41: 143: 42.13
+	Dm
		1249819 Q9VN02_DROME (1-220): 1.53e-50: 165: 24.32		CHM4_DROME (2-220): 2.1e-35: 127: 20.00
+	At
		1276050 VPS2C_ARATH (1-220): 3.63e-54: 174: 68.64		VP322_ARATH (1-224): 1.47e-31: 116: 25.89
+	At
		1013168 VPS2B_ARATH (1-222): 2.69e-53: 172: 100.00		VP322_ARATH (1-224): 1.47e-31: 116: 25.89
+	At
		1013164 VPS2A_ARATH (2-222): 6.22e-58: 184: 40.99		VPS2B_ARATH (7-230): 1.49e-25: 101: 16.07
+	Hs
		1330574 CHMP3_HUMAN (1-220): 1.47e-48: 160: 22.97		CHM4B_HUMAN (15-224): 2.71e-34: 124: 19.52
+	At
		287069 VPS2C_ARATH (1-220): 3.63e-54: 174: 68.64		VP321_ARATH (1-218): 7e-29: 109: 25.23
+	Sc
		732861 DID4_YEAST (3-221): 2.54e-51: 167: 33.04		VPS20_YEAST (6-225): 1.79e-31: 116: 22.17
+	At
		287066 VPS2B_ARATH (1-222): 2.69e-53: 172: 100.00		VP321_ARATH (1-218): 7e-29: 109: 25.23
+	Sc
		732840 DID4_YEAST (3-221): 2.54e-51: 167: 33.04		DID4_YEAST (7-223): 1.81e-30: 114: 13.76
+	Hs
		1316088 CHMP3_HUMAN (1-220): 1.47e-48: 160: 22.97		CHM4A_HUMAN (1-229): 9.87e-33: 119: 18.34
+	Sc
		732845 DID4_YEAST (3-221): 2.54e-51: 167: 33.04		SNF7_YEAST (3-214): 1.33e-29: 112: 16.90
+	At
		1209623 VPS2C_ARATH (1-220): 3.63e-54: 174: 68.64		VP201_ARATH (1-221): 1.39e-26: 104: 19.46
+	At
		1276045 VPS2C_ARATH (1-220): 3.63e-54: 174: 68.64		VP202_ARATH (1-220): 4.46e-26: 102: 19.09
+	At
		1013141 VPS2B_ARATH (1-222): 2.69e-53: 172: 100.00		VPS2B_ARATH (7-230): 1.49e-25: 101: 16.07
+	Sc
		732860 DID4_YEAST (3-221): 2.54e-51: 167: 33.04		VPS60_YEAST (1-195): 3.97e-26: 102: 25.12
+	Hs
		208872 CHMP3_HUMAN (1-220): 1.47e-48: 160: 22.97		CHM2A_HUMAN (1-185): 1.93e-28: 108: 17.80
+	Dm
		1362009 Q9VN02_DROME (1-220): 1.53e-50: 165: 24.32		Q9VBI3_DROME (7-200): 1.67e-25: 102: 15.00