HitPredict

Interactor 1: NEXN (Q0ZGT2)
Nexilin (F-actin-binding protein) (Nelin)
Gene: NEXN

Interactor 2: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~I-set
Common GO terms	GO:0030424 - axon
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 675 Hs			1 376
+	Hs
		891727 NEXN_HUMAN (1-675): 7.23e-105: 335: 100.00		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		932119 NEXN_HUMAN (1-675): 7.23e-105: 335: 100.00		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Hs
		915371 NEXN_HUMAN (1-675): 7.23e-105: 335: 100.00		ACTA_HUMAN (1-376): 0: 588: 87.80
+	Hs
		507933 FGFR1_HUMAN (349-674): 4.83e-41: 162: 13.51		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		507942 FGFR1_HUMAN (349-674): 4.83e-41: 162: 13.51		ACTG_HUMAN (3-376): 0: 595: 91.44
+	Hs
		507943 FGFR1_HUMAN (349-674): 4.83e-41: 162: 13.51		ACTS_HUMAN (2-376): 0: 590: 87.47
+	Hs
		891771 MYPC3_HUMAN (10-653): 5.58e-32: 135: 11.78		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		932159 MYPC3_HUMAN (10-653): 5.58e-32: 135: 11.78		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Hs
		891928 PALLD_HUMAN (573-675): 5.3e-11: 68.3: 23.08		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Mm
		250929 MYPC3_MOUSE (238-674): 4.61e-12: 71.8: 11.09		ACTC_MOUSE (2-376): 0: 590: 88.27
+	Dm
		54871 A1ZA72_DROME (357-675): 3.84e-10: 65.7: 13.08		ACT6_DROME (1-376): 0: 596: 88.83