HitPredict

Interactor 1: NEXN (Q0ZGT2)
Nexilin (F-actin-binding protein) (Nelin)
Gene: NEXN

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 675 Hs			1 759
+	Hs
		508252 FGFR1_HUMAN (349-674): 4.83e-41: 162: 13.51		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		508077 FGFR1_HUMAN (349-674): 4.83e-41: 162: 13.51		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		297718 VGFR1_HUMAN (527-673): 2.36e-31: 133: 22.73		MICA2_HUMAN (225-621): 5.97e-42: 167: 19.24
+	Hs
		508099 FGFR1_HUMAN (349-674): 4.83e-41: 162: 13.51		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150510 FGFR1_HUMAN (349-674): 4.83e-41: 162: 13.51		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150606 TITIN_HUMAN (591-672): 7.07e-09: 61.8: 18.29		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		1151801 TITIN_HUMAN (591-672): 7.07e-09: 61.8: 18.29		ABLM2_HUMAN (369-647): 1.72e-22: 104: 11.79