HitPredict

Interactor 1: SEH1 (Q10099)
Nucleoporin seh1 (Nuclear pore protein seh1)
Gene: SEH1

Interactor 2: NUP85 (Q9UUE5)
Nucleoporin nup85 (Nuclear pore protein nup85)
Gene: NUP85

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.854

Property	Details
Experiments	26771498, 15226438, 22955883
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Nucleopor_Nup85~WD40
Common GO terms	GO:0005634 - nucleus GO:0005643 - nuclear pore GO:0005829 - cytosol GO:0031080 - nuclear pore outer ring GO:0034399 - nuclear periphery
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 339 Sp			1 675
+	Hs
		1289593 SEH1_HUMAN (4-338): 1.41e-80: 251: 36.29		NUP85_HUMAN (81-610): 5.29e-156: 467: 17.39
+	Hs
		903486 WDR5_HUMAN (1-246): 2.69e-52: 177: 16.80		NUP85_HUMAN (81-610): 5.29e-156: 467: 17.39
+	Hs
		878241 SEC13_HUMAN (212-338): 6.58e-12: 67.5: 18.61		NUP85_HUMAN (81-610): 5.29e-156: 467: 17.39
+	Sc
		805086 SEH1_YEAST (2-213): 1.2e-11: 66.7: 11.97		NUP85_YEAST (34-605): 9.92e-147: 446: 19.18
+	Sc
		805096 SEC13_YEAST (8-92): 7.12e-09: 58.1: 21.35		NUP85_YEAST (34-605): 9.92e-147: 446: 19.18