HitPredict

Interactor 1: PSA4 (Q10329)
Probable proteasome subunit alpha type-4
Gene: pre6

Interactor 2: PSA5 (Q9UT97)
Probable proteasome subunit alpha type-5
Gene: pup2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20133687
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 259 Sp			1 247
+	Hs
		156230 PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59		PSA5_HUMAN (1-242): 4.18e-104: 303: 60.74
+	Hs
		637325 PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27		PSA5_HUMAN (1-242): 4.18e-104: 303: 60.74
+	Ss
		94704 F2Z5L7_PIG (2-259): 1.01e-93: 278: 27.27		F2Z5K2_PIG (1-242): 4.18e-104: 303: 60.74
+	Hs
		656149 PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03		PSA5_HUMAN (1-242): 4.18e-104: 303: 60.74
+	Ss
		94582 F1SBA5_PIG (2-226): 1.12e-97: 287: 55.51		F2Z5L7_PIG (3-245): 1.86e-90: 269: 34.82
+	Hs
		156169 PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59		PSA7_HUMAN (8-240): 3.63e-91: 270: 40.68
+	Hs
		156223 PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59		PSA1_HUMAN (3-245): 1.86e-90: 269: 34.82
+	Hs
		156266 PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59		PSA6_HUMAN (3-245): 1.6e-89: 266: 31.08
+	Hs
		156224 PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59		PSA2_HUMAN (3-243): 2.58e-89: 265: 32.37
+	Hs
		156328 PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59		PSMA8_HUMAN (6-240): 8.19e-89: 265: 36.89
+	Hs
		637315 PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27		PSA1_HUMAN (3-245): 1.86e-90: 269: 34.82
+	Hs
		637376 PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27		PSA6_HUMAN (3-245): 1.6e-89: 266: 31.08
+	Hs
		637316 PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27		PSA2_HUMAN (3-243): 2.58e-89: 265: 32.37
+	Hs
		637494 PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27		PSMA8_HUMAN (6-240): 8.19e-89: 265: 36.89
+	Hs
		637631 PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03		PSA2_HUMAN (3-243): 2.58e-89: 265: 32.37
+	Sp
		999716 PSA4_SCHPO (1-259): 2.44e-102: 299: 100.00		PSA3_SCHPO (3-224): 4.38e-44: 150: 39.56