Interactor 1: MKH1 (Q10407)
MAP kinase kinase kinase mkh1 (EC 2.7.11.25)
Gene: MKH1

Interactor 2: SKH1 (Q9Y884)
MAP kinase kinase skh1/pek1 (EC 2.7.12.2)
Gene: SKH1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.887

The method score is based on:

Property Details
Experiments 26771498, 27451356, 10591634, 23695164
Identification Methods two hybrid, affinity chromatography technology, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000196 - cell wall integrity MAPK cascade
GO:0000935 - division septum
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1116
Sp

1 363
+ Sc
+ Sc
+ At
+ At
+ At
+ At
+ Rn
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024