Interactor 1: F8VPR5 (F8VPR5)
histone acetyltransferase (EC 2.3.1.48)
Gene: Crebbp

Interactor 2: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 14759370, 20211142
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Creb_binding~P53_TAD, P53_TAD~zf-TAZ
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002039 - p53 binding
GO:0005667 - transcription regulator complex
GO:0005737 - cytoplasm
GO:0034644 - cellular response to UV
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 2441
Mm

1 390
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024