HitPredict

Interactor 1: F8VPR5 (F8VPR5)
histone acetyltransferase (EC 2.3.1.48)
Gene: Crebbp

Interactor 2: HES1 (P35428)
Transcription factor HES-1 (Hairy and enhancer of split 1)
Gene: HES1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15607978
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2441 Mm			1 282
+	Hs
		1270765 CBP_HUMAN (1-2441): 0: 1094: 94.89		HES6_HUMAN (11-280): 6.29e-44: 150: 24.82
+	Mm
		799605 CBP_MOUSE (1-2441): 0: 1114: 99.55		BMAL1_MOUSE (27-97): 1.76e-17: 83.9: 23.94
+	Hs
		126156 CBP_HUMAN (1-2441): 0: 1094: 94.89		BMAL1_HUMAN (27-97): 2.01e-17: 83.9: 23.94
+	Hs
		998977 EP300_HUMAN (1-2426): 0: 887: 54.94		HES6_HUMAN (11-280): 6.29e-44: 150: 24.82
+	Mm
		70944 EP300_MOUSE (1-2426): 0: 889: 53.65		BMAL1_MOUSE (27-97): 1.76e-17: 83.9: 23.94
+	Hs
		126124 EP300_HUMAN (1-2426): 0: 887: 54.94		BMAL1_HUMAN (27-97): 2.01e-17: 83.9: 23.94