HitPredict

Interactor 1: F8VPR5 (F8VPR5)
histone acetyltransferase (EC 2.3.1.48)
Gene: Crebbp

Interactor 2: CREB1 (Q01147)
Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1)
Gene: CREB1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	17525731, 7913207
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	KIX~pKID
Common GO terms	GO:0001223 - transcription coactivator binding GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2441 Mm			1 327
+	Mm
		799596 CBP_MOUSE (1-2441): 0: 1114: 99.55		CREB1_MOUSE (1-327): 2.51e-146: 416: 100.00
+	Hs
		556933 CBP_HUMAN (1-2441): 0: 1094: 94.89		CREB1_HUMAN (1-327): 6.86e-146: 415: 99.69
+	Hs
		974401 CBP_HUMAN (1-2441): 0: 1094: 94.89		CREM_HUMAN (1-327): 1.82e-133: 385: 60.23
+	Hs
		579154 CBP_HUMAN (1-2441): 0: 1094: 94.89		ATF1_HUMAN (72-326): 2.98e-94: 282: 65.13
+	Mm
		70912 EP300_MOUSE (1-2426): 0: 889: 53.65		CREB1_MOUSE (1-327): 2.51e-146: 416: 100.00
+	Hs
		556851 EP300_HUMAN (1-2426): 0: 887: 54.94		CREB1_HUMAN (1-327): 6.86e-146: 415: 99.69