Interactor 1: CANA (Q11002)
Calpain-A (EC 3.4.22.-) (Calcium-activated neutral proteinase A) (CANP A) [Cleaved into: Calpain-A catalytic subunit]
Gene: CalpA

Interactor 2: CANB (Q9VT65)
Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]
Gene: CalpB

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 30705102
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Calpain_III~Peptidase_C2, Peptidase_C2~Peptidase_C2
Common GO terms GO:0004198 - calcium-dependent cysteine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0016322 - neuron remodeling
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 828
Dm

1 925
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Rn
+ Hs
+ Hs
+ Hs
+ Zm
+ Dm
+ Ss

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Last updated: 15 Jul 2024