HitPredict

Interactor 1: MDN1 (Q12019)
Midasin (Dynein-related AAA-ATPase REA1) (MIDAS-containing protein) (Ribosome export/assembly protein 1)
Gene: MDN1

Interactor 2: YTM1 (Q12024)
Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1)
Gene: YTM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.665

Property	Details
Experiments	35147499, 20542003, 37968396
Identification Methods	pull down, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030687 - preribosome, large subunit precursor and 1 others more... GO:0110136 - protein-RNA complex remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4910 Sc			1 460
+	Sc
		630897 MDN1_YEAST (1-4910): 0: 4131: 100.00		NLE1_YEAST (19-130): 2.91e-11: 67.5: 15.28
+	Hs
		1068625 PLEC_HUMAN (3251-4833): 6.56e-37: 157: 8.60		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Hs
		724952 MYH9_HUMAN (2802-3632): 1.98e-25: 119: 8.49		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Hs
		792973 CENPE_HUMAN (3233-4902): 3.48e-50: 201: 8.80		LIS1_HUMAN (326-457): 9.83e-27: 113: 19.40
+	Hs
		725215 MYH10_HUMAN (4111-4747): 2.77e-19: 99.2: 16.02		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Hs
		551766 DESP_HUMAN (2663-3413): 7.48e-28: 127: 9.79		WDR5B_HUMAN (258-457): 6.29e-40: 147: 22.77
+	Hs
		551632 DESP_HUMAN (2663-3413): 7.48e-28: 127: 9.79		LIS1_HUMAN (326-457): 9.83e-27: 113: 19.40
+	Hs
		903240 PLEC_HUMAN (3251-4833): 6.56e-37: 157: 8.60		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		809094 UTRN_HUMAN (3211-4716): 5.6e-31: 138: 8.22		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		551870 DESP_HUMAN (2663-3413): 7.48e-28: 127: 9.79		FBW1A_HUMAN (101-246): 3.17e-19: 92.2: 19.65
+	Hs
		551854 DESP_HUMAN (2663-3413): 7.48e-28: 127: 9.79		NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24
+	Hs
		551659 DESP_HUMAN (2663-3413): 7.48e-28: 127: 9.79		GBB2_HUMAN (304-460): 7.32e-18: 86.3: 9.43
+	Hs
		551655 DESP_HUMAN (2663-3413): 7.48e-28: 127: 9.79		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		724753 MYH9_HUMAN (2802-3632): 1.98e-25: 119: 8.49		GBB2_HUMAN (304-460): 7.32e-18: 86.3: 9.43
+	Hs
		903212 SPTN1_HUMAN (3335-4651): 1.52e-19: 100: 8.58		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		1325953 MDN1_HUMAN (2169-2287): 4.99e-13: 78.8: 38.71		WDR12_HUMAN (286-458): 5.45e-20: 93.7: 17.95
+	Hs
		1345867 MDN1_HUMAN (2169-2287): 4.99e-13: 78.8: 38.71		FBW1A_HUMAN (101-246): 3.17e-19: 92.2: 19.65
+	Hs
		1345855 MDN1_HUMAN (2169-2287): 4.99e-13: 78.8: 38.71		NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24
+	Sp
		252177 MDN1_SCHPO (2165-2288): 3.1e-10: 69.5: 29.46		NLE1_SCHPO (362-458): 1.17e-17: 87.1: 22.45
+	Hs
		903607 MACF1_HUMAN (3565-4775): 6.86e-10: 68.4: 7.61		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49