HitPredict

Interactor 1: HPCA (P84074)
Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2)
Gene: HPCA

Interactor 2: DTX2 (Q86UW9)
Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2)
Gene: DTX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.665

Property	Details
Experiments	32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 622
+	Hs
		789647 HPCL1_HUMAN (1-193): 2.81e-60: 188: 94.30		DTX2_HUMAN (1-622): 0: 573: 100.00
+	Hs
		962901 NCALD_HUMAN (1-193): 3.56e-58: 182: 88.08		DTX2_HUMAN (1-622): 0: 573: 100.00
+	Hs
		1289336 HPCL4_HUMAN (1-189): 1.02e-48: 158: 67.02		DTX2_HUMAN (1-622): 0: 573: 100.00
+	Hs
		979420 VISL1_HUMAN (1-189): 9.66e-49: 158: 65.97		DTX2_HUMAN (1-622): 0: 573: 100.00
+	Hs
		968642 NCS1_HUMAN (1-187): 3.46e-47: 154: 58.82		DTX2_HUMAN (1-622): 0: 573: 100.00
+	Hs
		789679 HPCL1_HUMAN (1-193): 2.81e-60: 188: 94.30		DTX4_HUMAN (17-622): 9.2e-151: 450: 43.36