HitPredict

Interactor 1: YTM1 (Q12024)
Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1)
Gene: YTM1

Interactor 2: MAK21 (Q12176)
Ribosome biogenesis protein MAK21 (Maintenance of killer protein 21) (Nucleolar complex protein 1)
Gene: MAK21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	11805826, 36929751, 16429126, 35385737, 37968396, 23209026
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 460 Sc			1 1025
+	Hs
		977278 FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38		CEBPZ_HUMAN (43-1023): 0: 655: 26.37
+	Hs
		977321 NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24		CEBPZ_HUMAN (43-1023): 0: 655: 26.37
+	Hs
		977281 SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18		CEBPZ_HUMAN (43-1023): 0: 655: 26.37
+	Sc
		987684 YTM1_YEAST (1-460): 5.89e-107: 326: 100.00		NOC4_YEAST (306-801): 1.18e-103: 337: 15.98
+	Sc
		992546 YTM1_YEAST (1-460): 5.89e-107: 326: 100.00		NOC3_YEAST (124-769): 2.85e-92: 310: 13.15
+	Hs
		1259527 NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24		NOC3L_HUMAN (79-790): 2.08e-151: 471: 15.71
+	Hs
		1259496 SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18		NOC3L_HUMAN (79-790): 2.08e-151: 471: 15.71