HitPredict

Interactor 1: GGPPS (Q12051)
Geranylgeranyl pyrophosphate synthase BTS1 (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (BET2 suppressor protein 1) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)
Gene: BTS1

Interactor 2: GGPPS (Q12051)
Geranylgeranyl pyrophosphate synthase BTS1 (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (BET2 suppressor protein 1) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)
Gene: BTS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 18442135, 16554305, 19245203, 17535895
Identification Methods x-ray crystallography, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains polyprenyl_synt~polyprenyl_synt
Common GO terms GO:0004161 - dimethylallyltranstransferase activity
GO:0004311 - farnesyltranstransferase activity
GO:0004337 - geranyltranstransferase activity
GO:0004659 - prenyltransferase activity
GO:0005739 - mitochondrion
and 10 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 335
Sc

1 335
+ At
+ Hs
+ Hs
+ Sp
+ Ec
+ Hs
+ Sp
+ Hs
+ Sp
+ Ec
+ Hp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024