Interactor 1: LEU9 (Q12166)
2-isopropylmalate synthase 2, mitochondrial (EC 2.3.3.13) (Alpha-IPM synthase 2) (Alpha-isopropylmalate synthase 2) (Alpha-isopropylmalate synthase II)
Gene: LEU9

Interactor 2: LEU9 (Q12166)
2-isopropylmalate synthase 2, mitochondrial (EC 2.3.3.13) (Alpha-IPM synthase 2) (Alpha-isopropylmalate synthase 2) (Alpha-isopropylmalate synthase II)
Gene: LEU9

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.762

The method score is based on:

Property Details
Experiments 18719252, unassigned1933
Identification Methods two hybrid, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HMGL-like~HMGL-like, LeuA_dimer~LeuA_dimer
Common GO terms GO:0003852 - 2-isopropylmalate synthase activity
GO:0005739 - mitochondrion
GO:0008652 - amino acid biosynthetic process
GO:0009098 - L-leucine biosynthetic process
GO:0046872 - metal ion binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 604
Sc

1 604
+ Sc
+ Sc
+ Ss
+ Sc
+ Sc
+ Sc
+ Sp
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs

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Last updated: 15 Jul 2024