HitPredict

Interactor 1: F8VQD1 (F8VQD1)
Polybromo 1
Gene: Pbrm1

Interactor 2: SMCA2 (Q6DIC0)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: Smarca2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19279220
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0006338 - chromatin remodeling GO:0016514 - SWI/SNF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1704 Mm			1 1577
+	Hs
		846812 PB1_HUMAN (1-1704): 0: 1223: 97.30		SMCA2_HUMAN (1-1577): 0: 1051: 93.82
+	Mm
		101533 F8VQD1_MOUSE (1-1704): 0: 1238: 100.00		SMCA4_MOUSE (1-1575): 0: 999: 73.58
+	Hs
		847007 PB1_HUMAN (1-1704): 0: 1223: 97.30		SMCA4_HUMAN (1-1575): 0: 985: 72.61
+	Mm
		1111945 PB1_MOUSE (1-1704): 0: 1172: 92.61		SMCA4_MOUSE (1-1575): 0: 999: 73.58
+	Hs
		1059704 PB1_HUMAN (1-1704): 0: 1223: 97.30		CHD4_HUMAN (385-1537): 0: 738: 22.48
+	Hs
		1018557 PB1_HUMAN (1-1704): 0: 1223: 97.30		CHD3_HUMAN (310-1577): 0: 736: 22.41
+	Hs
		1199201 PB1_HUMAN (1-1704): 0: 1223: 97.30		CHD8_HUMAN (5-1402): 0: 718: 22.07
+	Dm
		631317 Q9VC36_DROME (1-1476): 0: 723: 34.46		BRM_DROME (68-1566): 0: 854: 49.59
+	Hs
		1199209 PB1_HUMAN (1-1704): 0: 1223: 97.30		CHD7_HUMAN (1-201): 6.62e-10: 66.7: 15.42
+	Hs
		600103 TAF1_HUMAN (457-978): 5.27e-60: 230: 15.81		SMCA2_HUMAN (1-1577): 0: 1051: 93.82
+	Hs
		847093 BRWD1_HUMAN (410-841): 5.22e-43: 175: 15.17		SMCA4_HUMAN (1-1575): 0: 985: 72.61
+	Hs
		229313 DNMT1_HUMAN (845-1310): 1.45e-65: 248: 14.23		SMCA5_HUMAN (589-1562): 0: 793: 26.67
+	Sp
		1336887 YK82_SCHPO (651-996): 1.65e-38: 157: 11.65		SNF21_SCHPO (438-1518): 0: 835: 41.62
+	Hs
		641217 DNMT1_HUMAN (845-1310): 1.45e-65: 248: 14.23		CHD4_HUMAN (385-1537): 0: 738: 22.48
+	Hs
		600135 TAF1_HUMAN (457-978): 5.27e-60: 230: 15.81		CHD3_HUMAN (310-1577): 0: 736: 22.41
+	Sc
		969433 RSC4_YEAST (331-882): 7.18e-43: 169: 14.75		ISW2_YEAST (584-1563): 0: 758: 27.47
+	Sc
		744895 RSC4_YEAST (331-882): 7.18e-43: 169: 14.75		ISW1_YEAST (614-1561): 0: 728: 29.09
+	Dm
		332801 Q8SX63_DROME (13-342): 1.1e-41: 171: 17.52		CHDM_DROME (330-1577): 0: 713: 21.18
+	Sc
		697424 RSC4_YEAST (331-882): 7.18e-43: 169: 14.75		CHD1_YEAST (670-1210): 1.54e-109: 384: 42.37
+	Sc
		696241 RSC4_YEAST (331-882): 7.18e-43: 169: 14.75		STH1_YEAST (1167-1494): 1.81e-23: 110: 14.33