HitPredict

Interactor 1: RUVB2 (Q12464)
RuvB-like protein 2 (RUVBL2) (EC 3.6.4.12) (TIP49-homology protein 2) (TIP49b homolog)
Gene: RVB2

Interactor 2: ARP6 (Q12509)
Actin-like protein ARP6
Gene: ARP6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26831523, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~TIP49
Common GO terms	GO:0000785 - chromatin GO:0000812 - Swr1 complex GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 471 Sc			1 438
+	Sc
		978062 RUVB1_YEAST (8-448): 0: 624: 41.10		ARP6_YEAST (1-438): 0: 921: 100.00
+	Sc
		887725 RUVB2_YEAST (1-471): 0: 707: 100.00		ACT_YEAST (2-432): 0: 529: 21.67
+	Hs
		930057 RUVB2_HUMAN (4-451): 0: 680: 68.15		ACTG_HUMAN (2-432): 0: 538: 20.32
+	Hs
		892121 RUVB2_HUMAN (4-451): 0: 680: 68.15		ACTB_HUMAN (2-432): 0: 536: 19.87
+	Hs
		932462 RUVB2_HUMAN (4-451): 0: 680: 68.15		ACTC_HUMAN (2-432): 0: 532: 20.54
+	Hs
		930058 RUVB1_HUMAN (10-448): 0: 658: 41.72		ACTG_HUMAN (2-432): 0: 538: 20.32
+	Hs
		892123 RUVB1_HUMAN (10-448): 0: 658: 41.72		ACTB_HUMAN (2-432): 0: 536: 19.87
+	Hs
		932463 RUVB1_HUMAN (10-448): 0: 658: 41.72		ACTC_HUMAN (2-432): 0: 532: 20.54
+	Dm
		501453 RUVB1_DROME (10-448): 0: 622: 40.18		ACT5_DROME (2-432): 0: 534: 20.09
+	Sc
		887667 RUVB1_YEAST (8-448): 0: 624: 41.10		ACT_YEAST (2-432): 0: 529: 21.67
+	Hs
		1326055 RUVB2_HUMAN (4-451): 0: 680: 68.15		ARP6_HUMAN (6-427): 4.31e-49: 173: 29.45
+	Hs
		1326056 RUVB1_HUMAN (10-448): 0: 658: 41.72		ARP6_HUMAN (6-427): 4.31e-49: 173: 29.45