HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: ELMO1 (Q92556)
Engulfment and cell motility protein 1 (Protein ced-12 homolog)
Gene: ELMO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.884

The method score is based on:

Property Details
Experiments 21930703, 22383878, 12879077, 33513601
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH_12~Ras
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007015 - actin filament organization
GO:0016601 - Rac protein signal transduction
GO:0030036 - actin cytoskeleton organization
and 3 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 191
Hs

1 727
+ Hs
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+ Ce
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Service provided by Combinatics, Japan

Last updated: 11Aug2025