HitPredict

Interactor 1: SCAP (Q12770)
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)
Gene: SCAP

Interactor 2: BT2A2 (Q8WVV5)
Butyrophilin subfamily 2 member A2
Gene: BTN2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	V-set~WD40
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1279 Hs			1 523
+	Hs
		1015986 SCAP_HUMAN (1-1279): 0: 1140: 100.00		BTNL8_HUMAN (32-503): 1e-95: 301: 32.01
+	Hs
		1108436 PTHD3_HUMAN (4-550): 1.14e-100: 345: 15.26		BT2A2_HUMAN (1-523): 3.93e-143: 424: 100.00
+	Hs
		1261870 PTC2_HUMAN (122-495): 2.76e-87: 311: 18.54		BT2A2_HUMAN (1-523): 3.93e-143: 424: 100.00
+	Hs
		1044365 PTC1_HUMAN (117-464): 1.6e-83: 302: 16.71		BT2A1_HUMAN (1-523): 1.04e-136: 407: 78.53
+	Hs
		167829 NPC1_HUMAN (7-549): 6.42e-121: 408: 20.48		TRI27_HUMAN (272-520): 7.11e-66: 223: 40.95
+	Hs
		373127 HMDH_HUMAN (276-489): 1.09e-53: 205: 24.19		BT2A1_HUMAN (1-523): 1.04e-136: 407: 78.53
+	Hs
		373125 HMDH_HUMAN (276-489): 1.09e-53: 205: 24.19		BTNL3_HUMAN (16-501): 6.22e-100: 311: 33.54
+	Hs
		585027 FBXW7_HUMAN (1104-1277): 2.9e-42: 168: 17.14		RO52_HUMAN (223-506): 1.32e-71: 237: 35.74
+	Hs
		585096 FBW1A_HUMAN (735-1033): 4.16e-42: 166: 12.90		RO52_HUMAN (223-506): 1.32e-71: 237: 35.74
+	Hs
		135035 FBXW7_HUMAN (1104-1277): 2.9e-42: 168: 17.14		TRI38_HUMAN (215-500): 6.81e-54: 190: 32.30
+	Hs
		585092 FBW1B_HUMAN (1149-1279): 3.89e-24: 110: 18.32		RO52_HUMAN (223-506): 1.32e-71: 237: 35.74
+	Hs
		1052726 FBXW7_HUMAN (1104-1277): 2.9e-42: 168: 17.14		TRI25_HUMAN (325-498): 5.34e-46: 172: 30.29