HitPredict

Interactor 1: F8VQL0 (F8VQL0)
Hepatocyte growth factor receptor (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (Tyrosine-protein kinase Met)
Gene: Met

Interactor 2: GAB1 (Q9QYY0)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	15314156
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1379 Mm			1 695
+	Mm
		555049 MET_MOUSE (1-1379): 0: 1386: 99.86		GAB1_MOUSE (1-695): 2.76e-116: 366: 100.00
+	Hs
		441499 MET_HUMAN (1-1379): 0: 1336: 89.43		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		441588 MET_HUMAN (1-1379): 0: 1336: 89.43		GAB2_HUMAN (3-692): 1.8e-86: 287: 37.09
+	Hs
		441420 MET_HUMAN (1-1379): 0: 1336: 89.43		MUC1_HUMAN (176-682): 2.08e-20: 98.8: 10.65
+	Hs
		981867 RON_HUMAN (23-1372): 0: 975: 33.57		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		981941 RON_HUMAN (23-1372): 0: 975: 33.57		PCLO_HUMAN (128-655): 2.32e-09: 63.3: 11.48
+	Hs
		872436 EPHA5_HUMAN (576-1364): 8.76e-171: 539: 18.84		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		872642 EPHA4_HUMAN (576-1375): 3.85e-162: 515: 18.04		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		665596 EPHB2_HUMAN (1019-1340): 6.01e-103: 355: 32.82		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		872492 EPHA5_HUMAN (576-1364): 8.76e-171: 539: 18.84		PKHA1_HUMAN (6-155): 3.11e-26: 113: 25.49
+	Hs
		872712 EPHA4_HUMAN (576-1375): 3.85e-162: 515: 18.04		PKHA1_HUMAN (6-155): 3.11e-26: 113: 25.49
+	Hs
		674415 UFO_HUMAN (1076-1331): 8.99e-66: 243: 45.90		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		435634 IGF1R_HUMAN (1082-1335): 7.76e-57: 218: 42.16		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		426958 FES_HUMAN (1080-1338): 7e-52: 199: 39.70		GAB1_HUMAN (1-695): 1.08e-115: 364: 90.22
+	Hs
		665662 EPHB2_HUMAN (1019-1340): 6.01e-103: 355: 32.82		PKHA1_HUMAN (6-155): 3.11e-26: 113: 25.49
+	Hs
		674531 UFO_HUMAN (1076-1331): 8.99e-66: 243: 45.90		PKHA1_HUMAN (6-155): 3.11e-26: 113: 25.49
+	Hs
		435768 IGF1R_HUMAN (1082-1335): 7.76e-57: 218: 42.16		PKHA1_HUMAN (6-155): 3.11e-26: 113: 25.49
+	Hs
		411498 INSR_HUMAN (1082-1333): 2.31e-55: 214: 42.11		PKHA1_HUMAN (6-155): 3.11e-26: 113: 25.49
+	Hs
		554307 ERBB4_HUMAN (1080-1338): 2.46e-52: 204: 42.42		MUC1_HUMAN (176-682): 2.08e-20: 98.8: 10.65