HitPredict

Interactor 1: SRBP2 (Q12772)
Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2 (Transcription factor SREBF2)]
Gene: SREBF2

Interactor 2: TRRAP (Q9Y4A5)
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)
Gene: TRRAP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22288532
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1141 Hs			1 3859
+	Hs
		739001 SRBP1_HUMAN (1-1141): 0: 870: 43.72		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		607852 USF1_HUMAN (223-408): 4.79e-26: 111: 20.20		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		738963 SRBP1_HUMAN (1-1141): 0: 870: 43.72		ATM_HUMAN (2081-3858): 0: 1072: 12.80
+	Hs
		998652 EP300_HUMAN (13-430): 1.85e-13: 77.7: 8.50		ATM_HUMAN (2081-3858): 0: 1072: 12.80
+	Mm
		1103464 MLXIP_MOUSE (1-419): 8.86e-34: 142: 13.58		MTOR_MOUSE (2163-3858): 0: 980: 14.80
+	Hs
		787572 MLXIP_HUMAN (10-426): 3.02e-28: 125: 11.63		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		787575 MLXPL_HUMAN (94-426): 5.27e-24: 111: 16.02		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		607807 USF1_HUMAN (223-408): 4.79e-26: 111: 20.20		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		787464 EP300_HUMAN (13-430): 1.85e-13: 77.7: 8.50		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		944204 EP300_HUMAN (13-430): 1.85e-13: 77.7: 8.50		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		998667 EP300_HUMAN (13-430): 1.85e-13: 77.7: 8.50		ATR_HUMAN (2569-3859): 0: 704: 15.07