Interactor 1: AKP13 (Q12802)
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)
Gene: AKAP13

Interactor 2: ARG28 (Q8N1W1)
Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor)
Gene: ARHGEF28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned2213
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains PH_16~PH_16, PH_16~RhoGEF, C1_1~RhoGEF, RhoGEF~RhoGEF
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0035023 - regulation of Rho protein signal transduction
GO:0046872 - metal ion binding
GO:0051056 - regulation of small GTPase mediated signal transduction
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 2813
Hs

1 1705
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Last updated: 15 Jul 2024