Interactor 1: KCNH2 (Q12809)
Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (H-ERG) (hERG-1) (hERG1) (Voltage-gated potassium channel subunit Kv11.1)
Gene: KCNH2

Interactor 2: KCND3 (Q9UK17)
Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3)
Gene: KCND3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29259226
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~cNMP_binding, Ion_trans~Ion_trans
Common GO terms GO:0005249 - voltage-gated potassium channel activity
GO:0005886 - plasma membrane
GO:0008076 - voltage-gated potassium channel complex
GO:0086009 - membrane repolarization
GO:0086013 - membrane repolarization during cardiac muscle cell action potential
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1159
Hs

1 655
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024