HitPredict

Interactor 1: RB40B (Q12829)
Ras-related protein Rab-40B (SOCS box-containing protein RAR) (Protein Rar)
Gene: RAB40B

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	26186194, 28514442, 33961781, 33999101, 34453716, 18187417, 21145461
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 278 Hs			1 780
+	Hs
		469822 RB40L_HUMAN (1-278): 3.79e-104: 306: 88.85		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1263839 RB40A_HUMAN (1-278): 6.15e-102: 300: 88.13		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Xl
		64998 Q5XHF6_XENLA (1-278): 6.53e-97: 287: 77.62		A7VK04_XENLA (1-780): 0: 793: 98.33
+	Hs
		1274024 RB40C_HUMAN (1-278): 8.54e-95: 282: 78.29		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Mm
		1257622 RB40C_MOUSE (1-278): 3.89e-94: 280: 78.65		CUL5_MOUSE (1-780): 0: 786: 98.46
+	Hs
		1042510 RAB1B_HUMAN (7-197): 1.37e-86: 258: 36.82		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		895481 RAB10_HUMAN (9-197): 3.44e-84: 252: 40.10		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		845850 RAB13_HUMAN (7-197): 7.91e-84: 251: 42.19		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1043210 RAB1B_HUMAN (7-197): 1.37e-86: 258: 36.82		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		886518 RAB15_HUMAN (9-178): 1.43e-47: 159: 45.61		CUL3_HUMAN (8-780): 0: 754: 22.96