HitPredict

Interactor 1: BPTF (Q12830)
Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)
Gene: BPTF

Interactor 2: HSPB7 (Q9UBY9)
Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp)
Gene: HSPB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 3046 Hs			1 170
+	Hs
		359089 TRI33_HUMAN (2455-3045): 2.57e-42: 173: 12.58		CRYAB_HUMAN (28-169): 1.17e-42: 141: 26.00
+	Hs
		170209 TIF1A_HUMAN (383-610): 8.36e-41: 168: 19.23		HSPB1_HUMAN (27-170): 1.44e-41: 139: 23.81
+	Hs
		358928 TRI33_HUMAN (2455-3045): 2.57e-42: 173: 12.58		CRYAA_HUMAN (45-169): 1.78e-39: 133: 23.13
+	Hs
		170199 TIF1A_HUMAN (383-610): 8.36e-41: 168: 19.23		CRYAA_HUMAN (45-169): 1.78e-39: 133: 23.13
+	Hs
		1080916 TRI33_HUMAN (2455-3045): 2.57e-42: 173: 12.58		HSPB2_HUMAN (38-153): 2.85e-36: 125: 28.57
+	Dm
		115973 M9PH39_DROME (2306-3033): 2.4e-37: 158: 11.63		HSP26_DROME (76-168): 3.23e-38: 131: 22.92
+	Hs
		359052 TITIN_HUMAN (1259-2946): 5.69e-25: 117: 7.72		CRYAB_HUMAN (28-169): 1.17e-42: 141: 26.00
+	Hs
		1264819 TITIN_HUMAN (1259-2946): 5.69e-25: 117: 7.72		HSPB8_HUMAN (26-169): 1.86e-37: 129: 27.70
+	Hs
		1080881 TITIN_HUMAN (1259-2946): 5.69e-25: 117: 7.72		HSPB2_HUMAN (38-153): 2.85e-36: 125: 28.57
+	Hs
		388627 CBP_HUMAN (1558-2670): 1.8e-12: 76: 8.05		HSPB1_HUMAN (27-170): 1.44e-41: 139: 23.81
+	Hs
		243781 BRD4_HUMAN (2936-3028): 1.03e-10: 70.1: 41.05		HSPB1_HUMAN (27-170): 1.44e-41: 139: 23.81