Interactor 1: M4K2 (Q12851)
Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)
Gene: MAP4K2
Interactor 2: M3K11 (Q16584)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)
Gene: MAP3K11
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11784851 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~Pkinase |
| Common GO terms | GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0006468 - protein phosphorylation GO:0007254 - JNK cascade GO:0031435 - mitogen-activated protein kinase kinase kinase binding and 3 others more... |
| Homologous interactions | 11 |
Homologous interactions
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Last updated: 15 Jul 2024
