HitPredict

Interactor 1: M4K2 (Q12851)
Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)
Gene: MAP4K2

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.50	0.512

Property	Details
Experiments	32640226
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 820 Hs			1 117
+	Hs
		891114 M4K2_HUMAN (1-820): 0: 877: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306141 M4K2_HUMAN (1-820): 0: 877: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		891118 STK4_HUMAN (3-421): 9.45e-121: 375: 33.89		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1023108 STK4_HUMAN (3-421): 9.45e-121: 375: 33.89		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306146 STK4_HUMAN (3-421): 9.45e-121: 375: 33.89		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		891124 STK3_HUMAN (3-291): 1.2e-118: 369: 43.10		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1027427 STK3_HUMAN (3-291): 1.2e-118: 369: 43.10		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306153 STK3_HUMAN (3-291): 1.2e-118: 369: 43.10		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1023104 STK4_HUMAN (3-421): 9.45e-121: 375: 33.89		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1023110 STK4_HUMAN (3-421): 9.45e-121: 375: 33.89		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1023105 STK4_HUMAN (3-421): 9.45e-121: 375: 33.89		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1027422 STK3_HUMAN (3-291): 1.2e-118: 369: 43.10		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1027430 STK3_HUMAN (3-291): 1.2e-118: 369: 43.10		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1027423 STK3_HUMAN (3-291): 1.2e-118: 369: 43.10		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		306314 SLK_HUMAN (11-274): 1.96e-66: 242: 45.32		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		296420 STK10_HUMAN (11-289): 8.66e-66: 238: 43.26		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21