Interactor 1: M3K12 (Q12852)
Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)
Gene: MAP3K12

Interactor 2: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 10490659
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH3_9
Common GO terms GO:0005737 - cytoplasm
GO:0007254 - JNK cascade
GO:0019901 - protein kinase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 859
Hs

1 824
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024