HitPredict

Interactor 1: NFIA (Q12857)
Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)
Gene: NFIA

Interactor 2: ETV7 (Q9Y603)
Transcription factor ETV7 (ETS translocation variant 7) (ETS-related protein Tel2) (Tel-related Ets factor) (Transcription factor Tel-2)
Gene: ETV7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Hs			1 341
+	Hs
		443275 NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61		ETV7_HUMAN (1-341): 8.53e-147: 419: 100.00
+	Hs
		135180 NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41		ETV7_HUMAN (1-341): 8.53e-147: 419: 100.00
+	Hs
		507411 NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00		ERG_HUMAN (9-304): 1.25e-83: 262: 25.77
+	Hs
		987770 NFIX_HUMAN (1-508): 9.66e-154: 449: 67.32		GABPA_HUMAN (33-331): 1.1e-82: 259: 22.85
+	Hs
		1018227 NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00		ELF2_HUMAN (133-336): 2.61e-56: 194: 22.97
+	Hs
		443120 NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61		ERG_HUMAN (9-304): 1.25e-83: 262: 25.77
+	Hs
		692129 NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00		ELF1_HUMAN (117-312): 1.29e-48: 174: 24.37
+	Hs
		1060291 NFIX_HUMAN (1-508): 9.66e-154: 449: 67.32		ELF2_HUMAN (133-336): 2.61e-56: 194: 22.97
+	Hs
		135069 NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41		ERG_HUMAN (9-304): 1.25e-83: 262: 25.77
+	Hs
		692137 NFIX_HUMAN (1-508): 9.66e-154: 449: 67.32		ELF1_HUMAN (117-312): 1.29e-48: 174: 24.37
+	Hs
		1018257 NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00		FEV_HUMAN (212-304): 2.51e-40: 143: 37.63
+	Hs
		443194 NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61		ELF2_HUMAN (133-336): 2.61e-56: 194: 22.97
+	Hs
		785358 NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00		ELK3_HUMAN (238-317): 3.57e-13: 71.6: 42.50
+	Hs
		443235 NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61		FEV_HUMAN (212-304): 2.51e-40: 143: 37.63
+	Hs
		135149 NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41		FEV_HUMAN (212-304): 2.51e-40: 143: 37.63
+	Dm
		669716 Q86P06_DROME (9-469): 1.66e-104: 331: 34.47		ETS3_DROME (171-304): 2e-45: 163: 28.99
+	Dm
		112023 L0MPW8_DROME (9-469): 5.22e-104: 329: 34.72		ETS3_DROME (171-304): 2e-45: 163: 28.99
+	Hs
		443145 NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61		ELK3_HUMAN (238-317): 3.57e-13: 71.6: 42.50
+	Hs
		135091 NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41		ELK3_HUMAN (238-317): 3.57e-13: 71.6: 42.50
+	Hs
		507468 KMT2C_HUMAN (183-506): 4.24e-10: 64.9: 9.12		ERG_HUMAN (9-304): 1.25e-83: 262: 25.77