HitPredict

Interactor 1: F8WI37 (F8WI37)
[histone H3]-lysine(4) N-methyltransferase (EC 2.1.1.364)
Gene: Kmt2c

Interactor 2: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23892456
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4904 Mm			1 305
+	Mm
		1194614 KMT2C_MOUSE (1-4904): 0: 2401: 99.98		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Hs
		620175 KMT2C_HUMAN (1-4904): 0: 2249: 84.59		PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81
+	Hs
		679137 KMT2C_HUMAN (1-4904): 0: 2249: 84.59		TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80
+	Hs
		839785 KMT2C_HUMAN (1-4904): 0: 2249: 84.59		LHX2_HUMAN (8-232): 1.48e-30: 120: 15.49
+	Hs
		641482 KMT2C_HUMAN (1-4904): 0: 2249: 84.59		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Hs
		822650 KMT2C_HUMAN (1-4904): 0: 2249: 84.59		LHX1_HUMAN (44-298): 6.25e-30: 118: 13.64
+	Hs
		213358 KMT2C_HUMAN (1-4904): 0: 2249: 84.59		TLX2_HUMAN (60-158): 3.78e-27: 108: 30.39
+	Hs
		211919 KMT2C_HUMAN (1-4904): 0: 2249: 84.59		TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08
+	Mm
		1142282 EZH2_MOUSE (4545-4886): 1.63e-78: 280: 22.73		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Mm
		1161071 CHD4_MOUSE (328-674): 2.18e-72: 273: 14.95		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Dm
		1359818 Q9W1H0_DROME (128-887): 2.86e-94: 342: 20.72		Q9V490_DROME (57-297): 1.43e-31: 125: 14.98
+	Mm
		1194616 NSD2_MOUSE (2-439): 1.14e-61: 237: 17.27		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Mm
		678763 CHD4_MOUSE (328-674): 2.18e-72: 273: 14.95		HXA2_MOUSE (2-305): 6.28e-42: 150: 19.03
+	Hs
		641393 CHD3_HUMAN (319-655): 9.67e-78: 291: 17.41		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Hs
		799104 CHD4_HUMAN (328-674): 3.91e-75: 283: 14.95		NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33
+	Mm
		788275 NSD2_MOUSE (2-439): 1.14e-61: 237: 17.27		NKX25_MOUSE (13-216): 2.84e-33: 126: 22.41
+	Dm
		1181739 TRR_DROME (102-337): 2.16e-29: 132: 16.53		Q7KS72_DROME (18-207): 8.44e-27: 109: 24.24
+	Dm
		1179567 Q7K3G5_DROME (358-434): 1.44e-13: 79: 42.50		Q9XZU0_DROME (88-289): 2.57e-32: 124: 14.29
+	Dm
		1179548 Q7K3G5_DROME (358-434): 1.44e-13: 79: 42.50		Q8T0V5_DROME (88-289): 5.41e-32: 123: 14.29
+	Ce
		880558 DPFF1_CAEEL (349-445): 8.81e-14: 78.6: 40.00		HM09_CAEEL (74-163): 2.45e-31: 116: 30.00