HitPredict

Interactor 1: CNTN1 (Q12860)
Contactin-1 (Glycoprotein gp135) (Neural cell surface protein F3)
Gene: CNTN1

Interactor 2: CEA21 (Q3KPI0)
Carcinoembryonic antigen-related cell adhesion molecule 21
Gene: CEACAM21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ig_3~fn3, V-set~fn3, Ig_3~I-set, I-set~V-set, Ig_3~ig, V-set~ig, Ig_3~Ig_3, Ig_3~V-set
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1018 Hs			1 293
+	Hs
		1108780 SDK2_HUMAN (73-992): 1.57e-48: 191: 14.96		CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00
+	Hs
		234601 DSCAM_HUMAN (3-986): 3.56e-92: 325: 15.82		ROBO1_HUMAN (126-282): 8.31e-22: 97.6: 15.39
+	Mm
		1149039 CNTN4_MOUSE (2-797): 8.65e-70: 254: 16.03		CNTN4_MOUSE (17-265): 3.1e-30: 121: 19.38
+	Hs
		489970 PTPRF_HUMAN (44-332): 2.53e-12: 73.6: 25.64		CEA21_HUMAN (1-293): 4.87e-75: 233: 100.00
+	Rn
		1144127 DCC_RAT (3-814): 3.21e-58: 221: 14.90		DCC_RAT (5-264): 2.59e-15: 78.3: 9.82
+	Rn
		222935 DCC_RAT (3-814): 3.21e-58: 221: 14.90		ROBO1_RAT (32-272): 1.69e-12: 69.9: 14.18
+	Hs
		685250 SDK2_HUMAN (73-992): 1.57e-48: 191: 14.96		CEAM8_HUMAN (5-253): 2.17e-20: 91.4: 15.56
+	Hs
		68222 PTPRF_HUMAN (44-332): 2.53e-12: 73.6: 25.64		HECA2_HUMAN (25-292): 2.84e-49: 171: 20.62
+	Mm
		936322 DSCAM_MOUSE (3-722): 2.68e-32: 138: 12.19		DCC_MOUSE (5-264): 2.01e-14: 75.6: 9.46
+	Ce
		103941 Q18100_CAEEL (171-746): 1.47e-09: 64.3: 20.47		SAX3_CAEEL (145-292): 1.19e-20: 94.1: 16.25
+	Hs
		1264775 NEO1_HUMAN (2-662): 1.05e-13: 77.8: 10.33		TITIN_HUMAN (62-258): 8.3e-09: 58.7: 13.89