HitPredict

Interactor 1: F8WIE5 (F8WIE5)
E3 ubiquitin-protein ligase (EC 2.3.2.26)
Gene: Hectd1

Interactor 2: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2610 Mm			1 734
+	Hs
		476559 HECD1_HUMAN (1-2610): 0: 2390: 98.93		UBC_HUMAN (77-724): 0: 790: 97.22
+	Mm
		476846 HERC4_MOUSE (1931-2609): 9.01e-164: 538: 18.63		UBC_MOUSE (1-734): 0: 912: 100.00
+	Mm
		477022 UBE3B_MOUSE (2063-2610): 3.69e-120: 411: 17.73		UBC_MOUSE (1-734): 0: 912: 100.00
+	Mm
		476862 UBR5_MOUSE (1986-2609): 3.4e-113: 407: 16.58		UBC_MOUSE (1-734): 0: 912: 100.00
+	Hs
		475871 HERC4_HUMAN (1931-2609): 1.75e-155: 514: 17.57		UBC_HUMAN (77-724): 0: 790: 97.22
+	Rn
		1140970 Q5YB86_RAT (2238-2608): 8.68e-113: 383: 21.24		UBC_RAT (1-724): 0: 898: 97.51
+	Dm
		89879 D5SHR3_DROME (2184-2609): 4.91e-115: 375: 20.44		UBIQP_DROME (1-686): 0: 873: 99.85
+	Hs
		475963 HECW1_HUMAN (1343-2609): 2.62e-130: 454: 14.01		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		304002 UBR5_HUMAN (1986-2609): 1.2e-111: 402: 16.83		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476205 ITCH_HUMAN (2238-2608): 2.87e-111: 380: 20.73		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476403 SMUF2_HUMAN (2235-2607): 2.11e-110: 373: 19.59		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476229 NED4L_HUMAN (2266-2608): 2.35e-106: 368: 21.78		UBC_HUMAN (77-724): 0: 790: 97.22
+	Dm
		1376481 Q9W325_DROME (2184-2609): 3.31e-117: 381: 20.89		Q9W418_DROME (1-458): 0: 588: 99.56
+	Sc
		477380 HUL5_YEAST (2013-2610): 2.11e-110: 378: 18.37		UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99
+	Hs
		398000 HERC4_HUMAN (1931-2609): 1.75e-155: 514: 17.57		ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69
+	Hs
		304113 UBR5_HUMAN (1986-2609): 1.2e-111: 402: 16.83		RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00
+	Hs
		475078 UBE3B_HUMAN (2063-2610): 4.33e-122: 417: 18.24		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		475140 ITCH_HUMAN (2238-2608): 2.87e-111: 380: 20.73		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		475196 SMUF2_HUMAN (2235-2607): 2.11e-110: 373: 19.59		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		125112 WWP2_HUMAN (2266-2608): 2.58e-105: 362: 24.93		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70