HitPredict

Interactor 1: MERTK (Q12866)
Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)
Gene: MERTK

Interactor 2: YTHD3 (Q7Z739)
YTH domain-containing family protein 3 (DF3)
Gene: YTHDF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 999 Hs			1 585
+	Hs
		1018378 MERTK_HUMAN (18-999): 0: 815: 100.00		YTHD2_HUMAN (1-581): 6.75e-156: 460: 65.81
+	Hs
		1018353 MERTK_HUMAN (18-999): 0: 815: 100.00		YTHD1_HUMAN (1-570): 2.77e-137: 412: 66.55
+	Hs
		665491 EPHA8_HUMAN (47-973): 0: 607: 18.38		YTHD3_HUMAN (1-568): 2.64e-171: 500: 100.00
+	Hs
		665521 EPHA8_HUMAN (47-973): 0: 607: 18.38		YTHD1_HUMAN (1-570): 2.77e-137: 412: 66.55
+	Hs
		600604 EPHA1_HUMAN (2-965): 2.9e-165: 512: 18.03		YTHD3_HUMAN (1-568): 2.64e-171: 500: 100.00
+	Hs
		972341 TIE2_HUMAN (87-859): 1.29e-155: 491: 22.06		YTHD3_HUMAN (1-568): 2.64e-171: 500: 100.00
+	Hs
		972367 TIE2_HUMAN (87-859): 1.29e-155: 491: 22.06		YTDC2_HUMAN (286-551): 2.37e-57: 210: 21.61
+	Hs
		302258 EPHA8_HUMAN (47-973): 0: 607: 18.38		SC31A_HUMAN (7-308): 3e-11: 68.8: 14.01
+	Hs
		169154 MUSK_HUMAN (4-864): 5.18e-172: 526: 20.22		SC31A_HUMAN (7-308): 3e-11: 68.8: 14.01
+	Hs
		302242 IGF1R_HUMAN (318-859): 5.21e-138: 449: 28.34		SC31A_HUMAN (7-308): 3e-11: 68.8: 14.01
+	Hs
		337532 ABL1_HUMAN (582-859): 9.16e-60: 224: 43.89		YTDC1_HUMAN (327-581): 1.19e-53: 196: 18.38
+	Hs
		302241 RET_HUMAN (584-858): 3.46e-58: 219: 39.39		SC31A_HUMAN (7-308): 3e-11: 68.8: 14.01
+	Hs
		981941 RON_HUMAN (535-861): 1.17e-59: 225: 37.95		PCLO_HUMAN (107-407): 4.6e-09: 61.8: 12.86