Interactor 1: PAN3 (G0S0Y3)
PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3)
Gene: PAN3

Interactor 2: PAN2 (G0SAK8)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Species: Thermochaetoides thermophila DSM 1495

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.831

The method score is based on:

Property Details
Experiments 24880343, 24872509
Identification Methods x-ray crystallography, molecular sieving, pull down, surface plasmon resonance, isothermal titration calorimetry
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pan3_PK~UCH_1
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0006397 - mRNA processing
GO:0031251 - PAN complex
GO:0046872 - metal ion binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 640
Tt

1 1170
+ Nc
+ Hs
+ Dm
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024