HitPredict

Interactor 1: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Interactor 2: PHF12 (Q96QT6)
PHD finger protein 12 (PHD factor 1) (Pf1)
Gene: PHF12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~PHD, PHD~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2000 Hs			1 1004
+	Hs
		1255040 CHD5_HUMAN (43-1961): 0: 1610: 66.45		PHF12_HUMAN (1-1004): 0: 1360: 100.00
+	Hs
		1109060 CHD9_HUMAN (20-1898): 0: 865: 22.10		PHF12_HUMAN (1-1004): 0: 1360: 100.00
+	Hs
		1018738 CHD3_HUMAN (1-2000): 0: 1917: 100.00		BAZ1B_HUMAN (1-239): 3.95e-32: 138: 15.52
+	Hs
		1017286 CHD3_HUMAN (1-2000): 0: 1917: 100.00		BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28
+	Hs
		1018602 CHD3_HUMAN (1-2000): 0: 1917: 100.00		CHD5_HUMAN (15-166): 1.47e-20: 100: 16.77
+	Hs
		1018483 CHD3_HUMAN (1-2000): 0: 1917: 100.00		CHD4_HUMAN (52-166): 3.04e-20: 99.6: 19.23
+	Hs
		1018442 CHD3_HUMAN (1-2000): 0: 1917: 100.00		CHD3_HUMAN (11-166): 1.58e-19: 97.3: 16.96
+	Hs
		1017327 CHD5_HUMAN (43-1961): 0: 1610: 66.45		BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28
+	Hs
		1059751 CHD5_HUMAN (43-1961): 0: 1610: 66.45		CHD4_HUMAN (52-166): 3.04e-20: 99.6: 19.23
+	Hs
		1059944 CHD4_HUMAN (132-1922): 0: 1552: 69.84		TRI33_HUMAN (33-272): 8.37e-33: 139: 16.47
+	Hs
		1059929 CHD4_HUMAN (132-1922): 0: 1552: 69.84		BAZ1B_HUMAN (1-239): 3.95e-32: 138: 15.52
+	Hs
		1017295 CHD4_HUMAN (132-1922): 0: 1552: 69.84		BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28
+	Hs
		1059928 CHD4_HUMAN (132-1922): 0: 1552: 69.84		BAZ2A_HUMAN (2-240): 1.87e-29: 129: 16.33
+	Hs
		1059813 CHD4_HUMAN (132-1922): 0: 1552: 69.84		RSF1_HUMAN (53-191): 9.33e-24: 110: 21.66
+	Hs
		1059614 CHD4_HUMAN (132-1922): 0: 1552: 69.84		CHD4_HUMAN (52-166): 3.04e-20: 99.6: 19.23
+	Dm
		332724 CHDM_DROME (78-1944): 0: 1408: 52.01		CHDM_DROME (50-278): 8.02e-29: 127: 16.47
+	Mm
		59026 CHD6_MOUSE (218-1804): 0: 886: 25.09		AIRE_MOUSE (50-114): 4.24e-15: 81.7: 41.54