HitPredict

Interactor 1: NMDE1 (Q12879)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A) (hNR2A)
Gene: GRIN2A

Interactor 2: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	9278515
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0014069 - postsynaptic density GO:0098839 - postsynaptic density membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1464 Hs			1 870
+	Rn
		962657 NMDE1_RAT (1-1464): 0: 1778: 95.22		DLG2_RAT (1-870): 0: 740: 94.94
+	Hs
		1028140 NMDE2_HUMAN (4-1464): 0: 1550: 52.95		DLG2_HUMAN (1-870): 0: 755: 100.00
+	Rn
		962666 NMDE2_RAT (4-1464): 0: 1537: 52.82		DLG2_RAT (1-870): 0: 740: 94.94
+	Mm
		761851 NMDE2_MOUSE (4-1464): 0: 1534: 52.82		ZO1_MOUSE (76-864): 1.64e-109: 372: 20.53
+	Mm
		723533 NMDE1_MOUSE (1-1464): 0: 1787: 95.29		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Rn
		962655 NMDE1_RAT (1-1464): 0: 1778: 95.22		DLG1_RAT (271-503): 5.38e-17: 87.9: 17.19
+	Rn
		677780 NMDE1_RAT (1-1464): 0: 1778: 95.22		DLG4_RAT (375-573): 1.69e-16: 86.4: 22.93
+	Rn
		962656 NMDE1_RAT (1-1464): 0: 1778: 95.22		DLG3_RAT (273-573): 1.44e-15: 83.3: 16.23
+	Hs
		1018888 NMDE1_HUMAN (1-1464): 0: 1763: 100.00		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		942334 NMDE1_HUMAN (1-1464): 0: 1763: 100.00		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Hs
		1018905 NMDE1_HUMAN (1-1464): 0: 1763: 100.00		DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40
+	Hs
		1021485 NMDE2_HUMAN (4-1464): 0: 1550: 52.95		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		942337 NMDE2_HUMAN (4-1464): 0: 1550: 52.95		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Rn
		962663 NMDE2_RAT (4-1464): 0: 1537: 52.82		DLG1_RAT (271-503): 5.38e-17: 87.9: 17.19
+	Hs
		1028145 NMDE2_HUMAN (4-1464): 0: 1550: 52.95		DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40
+	Rn
		677781 NMDE2_RAT (4-1464): 0: 1537: 52.82		DLG4_RAT (375-573): 1.69e-16: 86.4: 22.93
+	Mm
		963751 NMDE2_MOUSE (4-1464): 0: 1534: 52.82		DLG1_MOUSE (271-573): 6.98e-17: 87.6: 17.48
+	Rn
		962664 NMDE2_RAT (4-1464): 0: 1537: 52.82		DLG3_RAT (273-573): 1.44e-15: 83.3: 16.23
+	Mm
		963732 NMDE2_MOUSE (4-1464): 0: 1534: 52.82		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Mm
		936175 NMDE2_MOUSE (4-1464): 0: 1534: 52.82		DLG3_MOUSE (273-573): 2.97e-15: 82.5: 16.56