HitPredict

Interactor 1: SEPR (Q12884)
Prolyl endopeptidase FAP (EC 3.4.21.26) (170 kDa melanoma membrane-bound gelatinase) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)]
Gene: FAP

Interactor 2: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26209915
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0042803 - protein homodimerization activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 760 Hs			1 299
+	Hs
		648860 DPP4_HUMAN (4-758): 0: 797: 51.25		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		718803 SEPR_HUMAN (1-760): 0: 848: 100.00		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		646177 SEPR_HUMAN (1-760): 0: 848: 100.00		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		648663 DPP4_HUMAN (4-758): 0: 797: 51.25		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		718580 DPP6_HUMAN (2-760): 0: 770: 30.71		PHB1_HUMAN (22-280): 1e-85: 259: 51.15