Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29656893, 17043355
Identification Methods proximity labelling technology, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 53-BP1_Tudor~53-BP1_Tudor
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000776 - kinetochore
GO:0000781 - chromosome, telomeric region
GO:0002039 - p53 binding
GO:0003684 - damaged DNA binding
and 25 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1972
Hs

1 1972
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024