HitPredict

Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.698

The method score is based on:

Property Details
Experiments 29656893, 18986980, 30179224, 12607005
Identification Methods proximity labelling technology, affinity chromatography technology, pull down, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0016604 - nuclear body
GO:0035861 - site of double-strand break
and 2 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1972
Hs

1 2089
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024