HitPredict

Interactor 1: SEC13 (G0SA60)
Protein transport protein SEC13
Gene: SEC13

Interactor 2: NU145 (G0SAK3)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Species: Thermochaetoides thermophila DSM 1495

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23954503
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Nup96~WD40
Common GO terms	GO:0006606 - protein import into nucleus GO:0051028 - mRNA transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 308 Tt			1 1793
+	Hs
		857957 WDR5_HUMAN (140-308): 2.78e-34: 129: 16.57		NUP98_HUMAN (134-1752): 0: 653: 19.21
+	Hs
		857954 SEC13_HUMAN (1-112): 5.3e-10: 61.3: 24.39		NUP98_HUMAN (134-1752): 0: 653: 19.21
+	Dm
		1358850 WDS_DROME (140-308): 4.82e-33: 126: 14.20		NUP98_DROME (2-1750): 2.2e-165: 555: 18.73
+	Sc
		830669 SEH1_YEAST (12-306): 3.1e-68: 218: 26.15		NU145_YEAST (1295-1788): 4.32e-110: 385: 19.40
+	Sc
		858396 SEH1_YEAST (12-306): 3.1e-68: 218: 26.15		NU100_YEAST (1-992): 2.82e-35: 148: 17.96
+	Sc
		858397 SEH1_YEAST (12-306): 3.1e-68: 218: 26.15		NU116_YEAST (2-762): 1.78e-17: 91.1: 15.56
+	Sc
		774364 SEH1_YEAST (12-306): 3.1e-68: 218: 26.15		NU159_YEAST (2-388): 1.55e-11: 72.1: 14.21
+	Sc
		822983 SEH1_YEAST (12-306): 3.1e-68: 218: 26.15		NUP57_YEAST (6-219): 5.22e-11: 69.6: 27.97
+	Hs
		1244287 SNR40_HUMAN (143-304): 1.24e-25: 106: 16.56		ARI1B_HUMAN (5-1222): 2.76e-44: 179: 9.33
+	Hs
		1057782 FBXW7_HUMAN (45-307): 1.66e-54: 190: 16.29		NCOA6_HUMAN (92-1327): 5.95e-16: 86.6: 8.05
+	Hs
		1281391 FBXW7_HUMAN (45-307): 1.66e-54: 190: 16.29		PRR36_HUMAN (716-1334): 1.3e-11: 72.4: 10.72
+	Hs
		1056932 SNR40_HUMAN (143-304): 1.24e-25: 106: 16.56		MDC1_HUMAN (400-1337): 1.03e-32: 141: 10.87
+	Hs
		1288235 SNR40_HUMAN (143-304): 1.24e-25: 106: 16.56		P121A_HUMAN (5-668): 2.61e-23: 110: 12.43
+	Hs
		903229 WDR5_HUMAN (140-308): 2.78e-34: 129: 16.57		NCOA6_HUMAN (92-1327): 5.95e-16: 86.6: 8.05
+	Hs
		146265 SNR40_HUMAN (143-304): 1.24e-25: 106: 16.56		ARI1A_HUMAN (12-744): 9.47e-21: 102: 10.30
+	Mm
		903669 WDR5_MOUSE (140-308): 2.78e-34: 129: 16.57		KMT2C_MOUSE (178-1235): 6.85e-10: 66.6: 8.63
+	Sp
		292982 SEC13_SCHPO (164-291): 1.75e-16: 79.8: 23.85		NU189_SCHPO (2-591): 9.33e-23: 108: 15.37
+	Sp
		1013470 SEH1_SCHPO (17-214): 3.93e-13: 70.9: 15.70		NU189_SCHPO (2-591): 9.33e-23: 108: 15.37
+	Hs
		878229 SEC13_HUMAN (1-112): 5.3e-10: 61.3: 24.39		P121A_HUMAN (5-668): 2.61e-23: 110: 12.43
+	Hs
		727302 SEH1_HUMAN (208-294): 6.51e-10: 61.2: 23.60		NU214_HUMAN (1-398): 1.05e-12: 75.9: 19.61