Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: RN168 (Q8IYW5)
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168)
Gene: RNF168

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 25999347, 29656893
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0006974 - DNA damage response
GO:0035861 - site of double-strand break
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1972
Hs

1 571
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024