HitPredict

Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: SMRD1 (Q96GM5)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (SWI/SNF complex 60 kDa subunit)
Gene: SMARCD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29656893, 22990118
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0003712 - transcription coregulator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1972 Hs			1 515
+	Hs
		1019057 TP53B_HUMAN (1-1972): 0: 766: 100.00		SMRD2_HUMAN (51-515): 0: 601: 66.39
+	Hs
		1056934 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		SMRD1_HUMAN (1-515): 0: 696: 100.00
+	Hs
		1056868 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		SMRD3_HUMAN (60-515): 0: 613: 74.35
+	Dm
		1375096 ELYS_DROME (158-1224): 3.49e-18: 94: 11.64		BAP60_DROME (41-514): 0: 575: 63.48
+	Ce
		137245 MEL28_CAEEL (462-1118): 1.6e-20: 101: 15.40		SWIC2_CAEEL (79-514): 0: 523: 50.34