HitPredict

Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29656893
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1972 Hs			1 502
+	Hs
		826264 TP53B_HUMAN (1-1972): 0: 766: 100.00		CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69
+	Hs
		658914 TP53B_HUMAN (1-1972): 0: 766: 100.00		MK01_HUMAN (21-382): 7e-122: 362: 28.53
+	Hs
		414895 TP53B_HUMAN (1-1972): 0: 766: 100.00		CDK1_HUMAN (20-338): 2.76e-121: 358: 36.53
+	Hs
		807687 MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41		CDK3_HUMAN (17-357): 5.62e-127: 373: 36.52
+	Hs
		826275 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69
+	Hs
		625528 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		CDK2_HUMAN (17-345): 1.91e-130: 382: 36.04
+	Hs
		659014 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		MK01_HUMAN (21-382): 7e-122: 362: 28.53
+	Rn
		600341 MAP1A_RAT (6-1480): 1.91e-30: 134: 11.10		MK03_RAT (21-386): 4.81e-121: 361: 31.45
+	Hs
		625642 SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78		CDK2_HUMAN (17-345): 1.91e-130: 382: 36.04
+	Hs
		807640 MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41		CDK7_HUMAN (27-354): 7.4e-56: 191: 38.21
+	Hs
		841300 MINT_HUMAN (2-1787): 6.67e-46: 185: 7.93		CDK7_HUMAN (27-354): 7.4e-56: 191: 38.21