HitPredict

Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: MD2L2 (Q9UI95)
Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7)
Gene: MAD2L2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	29656893, 29160738
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0035861 - site of double-strand break GO:0045830 - positive regulation of isotype switching and 3 others more... GO:0045893 - positive regulation of DNA-templated transcription GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:2000042 - negative regulation of double-strand break repair via homologous recombination
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	1972
Hs

1	211

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024