Interactor 1: AIMP1 (Q12904)
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]
Gene: AIMP1

Interactor 2: SYK (Q15046)
Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)
Gene: KARS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.662

The method score is based on:

Property Details
Experiments 28514442, 33961781, 17443684
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000049 - tRNA binding
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 312
Hs

1 597
+ Ce
+ Sc
+ Hs
+ Dm
+ Sc
+ Sc
+ Ss

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024