HitPredict

Interactor 1: ILF3 (Q12906)
Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80)
Gene: ILF3

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	24457600, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 746
+	Mm
		1149807 ILF3_MOUSE (1-894): 0: 670: 84.97		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		1019512 ILF2_HUMAN (1-361): 4.06e-116: 361: 23.59		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		877285 DSRAD_HUMAN (341-681): 5.37e-44: 175: 20.00		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		331797 ILF3_HUMAN (1-894): 0: 687: 100.00		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		1019890 ILF3_HUMAN (1-894): 0: 687: 100.00		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Hs
		331783 RED1_HUMAN (337-610): 6.93e-37: 150: 34.29		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		322045 STAU1_HUMAN (341-766): 8.78e-37: 148: 18.88		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		323157 STAU1_HUMAN (341-766): 8.78e-37: 148: 18.88		EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27