HitPredict

Interactor 1: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr, PDZ~fn3, PDZ~SAM_1, PK_Tyr_Ser-Thr~Y_phosphatase, SAM_1~Y_phosphatase
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2485 Hs			1 998
+	Hs
		872638 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		872431 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		665393 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA3_HUMAN (25-990): 0: 1189: 62.01
+	Hs
		665589 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		665228 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		600564 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA1_HUMAN (10-986): 0: 975: 44.30
+	Hs
		665554 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		665158 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665220 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		600558 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		EPHA1_HUMAN (10-986): 0: 975: 44.30
+	Hs
		411297 PTPRB_HUMAN (953-2481): 3.7e-135: 473: 14.59		INSR_HUMAN (284-953): 2.01e-145: 470: 24.71
+	Hs
		616913 PTPRB_HUMAN (953-2481): 3.7e-135: 473: 14.59		TIE2_HUMAN (331-896): 1.04e-144: 462: 28.77
+	Hs
		505564 EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		674528 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		411369 PTPRJ_HUMAN (1183-2475): 1.09e-110: 389: 14.37		INSR_HUMAN (284-953): 2.01e-145: 470: 24.71
+	Hs
		411363 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		INSR_HUMAN (284-953): 2.01e-145: 470: 24.71
+	Hs
		204618 E41L2_HUMAN (367-1065): 2.11e-113: 389: 17.33		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		674402 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		972322 PTPRJ_HUMAN (1183-2475): 1.09e-110: 389: 14.37		TIE2_HUMAN (331-896): 1.04e-144: 462: 28.77
+	Hs
		412146 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45