HitPredict

Interactor 1: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Interactor 2: KSR1 (Q8IVT5)
Kinase suppressor of Ras 1 (EC 2.7.11.1)
Gene: KSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Y_phosphatase
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2485 Hs			1 923
+	Hs
		665393 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA3_HUMAN (206-888): 1.72e-170: 523: 14.58
+	Hs
		872638 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA4_HUMAN (206-912): 6.5e-164: 506: 14.77
+	Hs
		665589 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHB2_HUMAN (223-895): 5.19e-149: 469: 14.82
+	Hs
		872431 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA5_HUMAN (223-888): 4.57e-149: 469: 14.15
+	Hs
		1020163 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA7_HUMAN (215-914): 9.83e-149: 467: 14.59
+	Hs
		665228 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA2_HUMAN (223-917): 2.52e-144: 454: 14.62
+	Hs
		374139 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03
+	Hs
		600564 PTN13_HUMAN (1-2485): 0: 1895: 100.00		EPHA1_HUMAN (223-917): 1.29e-138: 439: 15.72
+	Hs
		411696 PTN13_HUMAN (1-2485): 0: 1895: 100.00		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59
+	Hs
		719535 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		KSR1_HUMAN (1-923): 0: 765: 100.00
+	Hs
		665554 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		EPHB2_HUMAN (223-895): 5.19e-149: 469: 14.82
+	Hs
		488594 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		ARAF_HUMAN (261-899): 1.38e-148: 454: 24.55
+	Hs
		665158 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		EPHA2_HUMAN (223-917): 2.52e-144: 454: 14.62
+	Hs
		665220 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		EPHA2_HUMAN (223-917): 2.52e-144: 454: 14.62
+	Hs
		204591 E41L2_HUMAN (367-1065): 2.11e-113: 389: 17.33		RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03
+	Hs
		373784 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03
+	Hs
		600558 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		EPHA1_HUMAN (223-917): 1.29e-138: 439: 15.72
+	Hs
		411596 PTPRB_HUMAN (953-2481): 3.7e-135: 473: 14.59		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59
+	Hs
		411855 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59
+	Hs
		411695 PTPRJ_HUMAN (1183-2475): 1.09e-110: 389: 14.37		LCK_HUMAN (591-890): 2.14e-99: 322: 24.59